The joke is that Portland is divided into 5 quadrants. (Get it, 5 QUADrants. Hardy, har!) But, the only thing that matters to Portlanders is - which side of the river do you live on?
The only time any of my home buyers wonder if they should find a home east or west of the Willamette is when they're moving in from out of town. Just about anyone that lives in Portland, or the surrounding suburbs, already has definitive opinions about which side is "best". Meaning, of course, which side is best for them.
I could say something very Realtor-ish, like, "I enjoy both east and west Portland equally for their diverse differences. Really, I do!"
Where's the fun in that, though? Of course I have a preference. However, I'm not going to tell you where I fall in the great debate! You're just going to have to guess which side I like more after reading my blog.